{"id":22,"date":"2015-05-06T13:40:08","date_gmt":"2015-05-06T12:40:08","guid":{"rendered":"http:\/?page_id=22"},"modified":"2022-09-08T13:20:14","modified_gmt":"2022-09-08T12:20:14","slug":"perspectives","status":"publish","type":"page","link":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/?page_id=22","title":{"rendered":"Prospective"},"content":{"rendered":"<p><\/p>\n<h3>Prospects for the years to come<\/h3>\n<p style=\"text-align: justify;\"><strong>1.<\/strong><u><\/u><strong> <u>Risk factors<\/u><\/strong><u>.<\/u>The laboratory coordinates an international consortium Eranet-Neuron targeting adolescent neurocognitive processes in depression to promote intervention response : <a href=\"https:\/\/www.neuron-eranet.eu\/_media\/ADORe_summary.pdf\">https:\/\/www.neuron-eranet.eu\/_media\/ADORe_summary.pdf<\/a>At-risk adolescents, young adults, and patients hospitalized for disorders tacking on emotional dysregulation or addiction will be investigated with respect to developmental databases.Since some mental disorders might be linked with measurable changes in brain structure development, investigations will focus on subject&nbsp; at-risk&nbsp; for affective disorders, or for addictions (e.g. binge drinking), or with autism spectrum disorders.<\/p>\n<p><strong>Example : Dynamic Functional Connectivity in Adolescence<\/strong><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/image-DFC.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-1522\" src=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/image-DFC-248x300.jpg\" alt=\"\" width=\"248\" height=\"300\" srcset=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/image-DFC-248x300.jpg 248w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/image-DFC.jpg 487w\" sizes=\"(max-width: 248px) 100vw, 248px\" \/><\/a><a href=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/static-networks.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-1523\" src=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/static-networks-296x300.jpg\" alt=\"\" width=\"296\" height=\"300\" srcset=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/static-networks-296x300.jpg 296w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/static-networks.jpg 487w\" sizes=\"(max-width: 296px) 100vw, 296px\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/www.inserm.fr\/actualite\/sante-mentale-de-la-desynchronisation-a-la-depression\/\"><span style=\"color: #3366ff;\">https:\/\/www.inserm.fr\/actualite\/sante-mentale-de-la-desynchronisation-a-la-depression\/<\/span><\/a><\/p>\n<p style=\"text-align: center;\"><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34051395\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34051395\/<\/a><\/span><\/p>\n<p>2.&nbsp;<span style=\"text-decoration: underline;\"><strong>New models in high-risk individuals<\/strong><\/span> (click to enlarge) :<\/p>\n<p><a href=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/whelan-galino_1.png\"><img decoding=\"async\" loading=\"lazy\" class=\" wp-image-1548 aligncenter\" src=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/whelan-galino_1-300x169.png\" alt=\"\" width=\"476\" height=\"268\" srcset=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/whelan-galino_1-300x169.png 300w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/whelan-galino_1-1024x576.png 1024w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/whelan-galino_1-768x432.png 768w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/whelan-galino_1.png 1307w\" sizes=\"(max-width: 476px) 100vw, 476px\" \/><\/a><\/p>\n<p style=\"text-align: justify;\">3.<strong> <u>Pharmaceutics &amp; drug response<\/u><\/strong>. Objective brain descriptors of drugs effects will be searched, based on our experience of controlled therapeutic trials involving imaging patients with depression or schizophrenia.<\/p>\n<p style=\"text-align: left;\">4. <span style=\"text-decoration: underline;\"><strong>Search for brain descriptors<\/strong><\/span> of response or resistance to therapy or addiction : <a style=\"font-size: revert;\" href=\"https:\/\/centreborelli.ens-paris-saclay.fr\/fr\/trajectoires-developpementales-psychiatrie\"><span style=\"color: #3366ff;\">https:\/\/centreborelli.ens-paris-saclay.fr\/fr\/trajectoires-developpementales-psychiatrie<\/span><\/a><\/p>\n\n\n<p>\u00a0<\/p>\n<p><a href=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/resilents-polytox-GP-.jpeg\"><img decoding=\"async\" loading=\"lazy\" class=\" wp-image-1508 aligncenter\" src=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/resilents-polytox-GP--300x120.jpeg\" alt=\"\" width=\"430\" height=\"172\" srcset=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/resilents-polytox-GP--300x120.jpeg 300w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/resilents-polytox-GP--1024x409.jpeg 1024w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/resilents-polytox-GP--768x307.jpeg 768w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/resilents-polytox-GP--1536x613.jpeg 1536w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/resilents-polytox-GP-.jpeg 1978w\" sizes=\"(max-width: 430px) 100vw, 430px\" \/><\/a><a href=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/classification-ados-resilents-.png\"><img decoding=\"async\" loading=\"lazy\" class=\" wp-image-1511 aligncenter\" src=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/classification-ados-resilents--300x147.png\" alt=\"\" width=\"420\" height=\"206\" srcset=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/classification-ados-resilents--300x147.png 300w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/classification-ados-resilents--1024x503.png 1024w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/classification-ados-resilents--768x377.png 768w, https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/wp-content\/uploads\/2022\/05\/classification-ados-resilents-.png 1388w\" sizes=\"(max-width: 420px) 100vw, 420px\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33770525\/\"><span style=\"color: #3366ff;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33770525\/<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prospects for the years to come 1. Risk factors.The laboratory coordinates an international consortium Eranet-Neuron targeting adolescent neurocognitive processes in depression to promote intervention response : https:\/\/www.neuron-eranet.eu\/_media\/ADORe_summary.pdfAt-risk adolescents, young adults, and patients hospitalized for disorders tacking on emotional dysregulation or addiction will be investigated with respect to developmental databases.Since some mental disorders might be linked &hellip; <a href=\"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/?page_id=22\" class=\"more-link\">Continuer la lecture de <span class=\"screen-reader-text\">Prospective<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":14,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=\/wp\/v2\/pages\/22"}],"collection":[{"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=22"}],"version-history":[{"count":36,"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=\/wp\/v2\/pages\/22\/revisions"}],"predecessor-version":[{"id":2044,"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=\/wp\/v2\/pages\/22\/revisions\/2044"}],"up":[{"embeddable":true,"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=\/wp\/v2\/pages\/14"}],"wp:attachment":[{"href":"https:\/\/www.inserm-u1000.universite-paris-saclay.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=22"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}